李 燕，鲍治成，杨冉冉，王忠一

（烟台市食品药品检验检测中心，山东烟台 264003）

摘要：试验建立了QuEChERS 净化-气相色谱/三重四极杆质谱仪检测酱油中6种对羟基苯甲酸酯类含量的方法。样品经盐酸酸化、乙腈提取、QuEChERS净化，用气相色谱/三重四极杆质谱仪检测，外标法定量。本方法实验条件下，对羟基苯甲酸酯类在0.02～5.0 mg/L范围内呈良好线性关系，相关系数r²≥0.999 1；样品中加标回收率为78.3%～101.3%，相对标准偏差介于1.5%～4.2%，对羟基苯甲酸酯类的检出限为0.01 mg/kg。该方法操作简便，重现性好，且准确度、灵敏度高。

关键词：QuEChERS；对羟基苯甲酸酯类；气相色谱-三重四极杆质谱法；酱油

中图分类号：TS207.3   文献标识码：A   文章编号：1674-506X（2023）04-0151-0005

Determination of 6 Parabens in Soy Sauce by QuEChERS Purification GC-MS/MS

LI Yan, BAO Zhicheng, YANG Ranran, WANG Zhongyi

（Yantai Testing Center for Food and Drug Control, Yantai Shandong 264003, China）

Abstract：A QuEChERS purification GC-MS/MS method was established for the determination of 6 parabens in soy sauce. The samples were acidified by hydrochloric acid, extracted by acetonitrile, purified by QuEChERS, detected by GC-MS/MS, and quantified by external standard method. Under the experimental conditions of this method, there was a good linear relationship between parabens in the range of 0.02～5.0 mg/L, and the correlation coefficient r²≥0.999 1. The recoveries ranged from 78.3% to 101.3%, and the relative standard deviations ranged from 1.5% to 4.2%. The detection limits of parabens were 0.01 mg/kg. This method is simple in operation, good in reproducibility, high in accuracy and sensitivity.

Keywords：QuEChERS; parabens; gas chromatography-triple quadrupole mass spectrometry （GC-MS/MS）; soy sauce

doi：10.3969/j.issn.1674-506X.2023.04-024

收稿日期：2023-03-29

作者简介：李燕（1976-），女，硕士，高级工程师。研究方向：食品安全与检测。

引文格式：李燕,鲍治成,杨冉冉,等.QuEChERS净化-气相色谱/三重四极杆质谱法测定酱油中6种对羟基苯甲酸酯类[J].食品与发酵科技,2023,59(04):151-155.